QLS

Europe/Rome 2019-02-22 11:00:00 2019-02-22 12:00:00 Mathematical modelling of red blood cell development A requisite to understand the general principles underlying transcriptional regulation is to define its most important players (i.e. transcription factors and cofactors) quantitatively in absolute terms. Such global and quantitative knowledge is necessary to define the range of possibilities (i.e. the general context) within which TFs perform their functions from interacting to forming complexes, to being recruited to specific genes in specific nuclear environment. Furthermore, competition between TFs (for binding sites) is thought to be an important mechanism for driving cellular differentiation with changes in the stoichiometry between LS-TFs being considered as the central mechanism underlying cell fate choice.   We measure RNA-seq (transcriptomic) expression and SRM (proteomic) of a time series hematopietic stem cells differentiation into red blood cells. To study the data, first we perform a bioinformatics analysis of our samples to identify the most relevant genes. Second, we build a Gene Regulatory Network (GRN) of those genes based on previous knowledge and correlations in our time series. Third, we transform that GRN into a system of Ordinary Differential Equations to obtain a quantitative model. Fourth, we perform some knock-down experiments to validate our model. Our results show new interactions between genes and an accurate quantitative description of red blood cell development. ICTP ICTP pio@ictp.it 22 Feb 2019

Europe/Rome 2019-02-25 07:00:00 2019-03-22 21:00:00 Spring College on the Physics of Complex Systems | (smr 3274) ICTP and SISSA, in collaboration with the partner institutions of the International Master Course in Physics of Complex Systems organize the Spring College on the Physics of Complex Systems from 25 February to 22 March 2019. Many complex systems in physics, biology, engineering and economics are characterized by a large number of interacting degrees of freedom giving rise to a non-trivial collective behavior. The theoretical and computational tools for a quantitative analysis of complex systems are often rooted in modern (statistical, quantum) physics. The Spring College on the Physics of Complex Systems gives students the opportunity to get in touch with a selection of topics at the forefront of research during an intensive 4-week program. It consists of 5 courses of 9 lectures each, followed by final written tests. Lecturers and Courses:   Deepak DHAR (IISER, Pune, India) Self-Organized Criticality   Henri ORLAND (CEA, France) Electrostatic Interactions in Soft and Biological Matter   Shahin ROUHANI (Sharif U., Tehran, Iran) Statistical Mechanics of Two Dimensional Critical Curves Mukund THATTAI (NCBS, Bangalore, India) Randomness in Biology Bence TOTH (Capital Fund Management, Paris, France) Elements of Quantitative Finance   Students and young researchers from all countries that are members of the United Nations, UNESCO or IAEA may apply for the College. Candidates are required to solicit recommendation letters to be sent by their supervisors in support of their application. Participants should have an adequate working knowledge of English. As a rule, travel and subsistence expenses of the participants should be borne by their home institutions. However, limited funds are available to partially support some participants, who are nationals of, and working in, a developing country, and who are not more than 45 years old. Such support is limited and candidates should make every effort to secure support for their travel, at least partial. Attendance of lectures and completion of the final written tests are mandatory for those who are granted ICTP funding. There is no registration fee. RULES FOR PARTICIPATION Participants with financial support from the ICTP and Master PCS students are  required to attend at least 80% of the courses. Attendance is monitored regularly. Taking the final exam for each course is mandatory for participants with financial support from the ICTP and Master PCS students. Grading system: Each course will be graded on a scale from 0 to 20. Marks higher than 10 correspond to pass. A final grade will be given for the overall Spring College with the following scale: E- Excellent - 5 exams passed A- Very Good - 4 exams passed B- Good - 3 exams passed C- Sufficient - 2 exams passed F- Fail - 1 or no exams passed The overall grade of participants will be published on the Spring College webpage. Certificates of attendance will be awarded only to participants who have attended at least 80% of the courses, with no exception.   ICTP ICTP pio@ictp.it 25 Feb 2019 - 22 Mar 2019

Europe/Rome 2019-07-10 08:00:00 2019-07-12 22:00:00 Workshop on Locomotion and Navigation from Flies to Robots | (smr 3309) Animals have to move in order to accomplish fundamental tasks such as foraging, migration and mating. They navigate the environment by collecting information through their senses, integrating the different inputs and generating a motor response that finally results in efficient search strategies. How do different organisms solve similar problems? Are there unifying principles? How are neural circuits organized so as to direct appropriate behavior? Can animal behavior provide useful inspiration for robotics applications? Can results from decision-making theory improve our understanding of animal behavior? How can physical and mathematical modeling contribute to advance our knowledge? This workshop aims at gathering physicists, biologists, neuroscientists, and computer scientists to offer their diverse perspectives and explore new directions for research and opportunities for collaborations in this rapidly developing field.   Invited Speakers include: Jelle ATEMA, Boston U. Mahesh M. BANDI, OIST Gordon BERMAN, Emory U. Vikas BHANDAWAT, Duke U. Ring CARDÉ, UC Riverside Jérôme CASAS, U. Tours Maria DACKE, Lund U. Ofer FEINERMAN, Weizmann Andrea FLACK, MPI Anna GAGLIARDO, U. Pisa Daniel GOLDMAN, Gerogia Tech Nick GRAVISH, UC San Diego David L. HU, Georgia Tech Vivek JAYARAMAN, Janelia Ryohei KANZAKI, U. Tokyo Henrik MOURITSEN, Oldenburg U. Katherine NAGEL, NYU Ran NATHAN, The Hebrew U. of Jerusalem Sharad RAMANATHAN, Harvard U. Aravinthan D.T. SAMUEL, Harvard U. Greg J. STEPHENS, VU Amsterdam Henri WEIMERSKIRCH, CNRS Chizé   ICTP ICTP pio@ictp.it 10 Jul 2019 - 12 Jul 2019

Europe/Rome 2019-09-11 08:00:00 2019-09-14 22:00:00 ECRO 2019 Conference of the European Chemoreception Research Organization | (smr 3321) For more information and to submit your application visit https://www.ecro.online/meetings/ecro-2019-trieste/ A limited number of ICTP grants are available to support the attendance of selected participants - particularly scientists at the early stages of their career - from developing countries (see list here) ICTP gants can cover local costs and/or travel costs. ICTP encourages the participation of female scientists. Deadline to apply for ICTP grants: 10 June 2019   ICTP ICTP pio@ictp.it 11 Sep 2019 - 14 Sep 2019

Europe/Rome 2019-09-30 08:00:00 2019-10-04 22:00:00 Workshop on Science of Data Science | (smr 3283) The workshop aims at gathering active scientists from different domains (statistics, machine learning, statistical physics, computer science) who made significant contributions in order to address conceptual questions in Data Science, where a unified, well accepted picture is still lacking   CALL FOR APPLICATIONS OPENING SOON   ICTP ICTP pio@ictp.it 30 Sep 2019 - 4 Oct 2019